What Are the Treatments for Candida Albicans on the Skin?
Candida albicans is a species of yeast that is implicated in up to 80 percent of all Candida infections. Overgrowth of Candida albicans on the skin occurs when immune system function is compromised, or the body's "good" flora and fauna is upset, or when poor hygiene is practiced. Candida albicans prefers warm, moist, covered regions of the body, such as the armpits, groin, cleft of the buttocks, and under large folds of skin and the nail-beds. There are different types of topical antimicrobials used to treat Candida albicans on the skin, some of which are natural preparations.
Fluconazole is a generic drug that belongs to a group of antifungals called, triazoles, which are regarded as the most effects medicines in dealing with candidiasis of the skin and mouth, according to Fungusfocus.com. Fluconazole, which is the active ingredient in the brand-name drug, Diflucan, is considered a fungistatic agent, which inhibits the growth cycle of the Candida albicans. Fluconazole is usually used for vaginal candidiasis and oral thrush, but can be used on the skin as a solution. Some Candida albican strains have developed resistance to fluconazole. Fluconazole is offered as solution, cream and tablets.
Itraconazole is another generic drug considered a triazole and fungistatic agent, and is marketed as the brand-name drug, Sporanox. Itraconazole is widely used to treat Candida and other fungal infections of the fingernails and toenails, which is called onychomycoses, as cited by the Merck Manual. Itraconazole is offered as capsules and solution.
Ketoconazole is a generic antifungal found in the name-brand drug, Nizoral, and is classified as an imidazole, which has the reputation for being very toxic to the liver. Ketoconazole is also a fungistatic agent and is particularly effective against Candida albicans of the skin and mouth, although it is now used less due to its toxicity Ketoconazole, according to "Fungal Infection: Diagnosis and Management.". Ketoconazole is offered as a cream, shampoo and tablet.
Clotrimazole is also an imidazole type drug, but it acts as a fungicidal agent, which kills Candida albicans on contact by rupturing its cell wall, as cited on Fungusfocus. Clotrimazole is the active ingredient in, Mycelex, which is an effective over-the-counter cream for topical candidiasis.
Miconazole is also a generic fungicidal agent classified as an imidazole, and is the main component in the brand-name drug, Monistat. Miconazole is fungicidal at high doses only, and is most effective as an oral rinse for thrush, but it does work well as a cream and gel on skin candidiasis.
Nystatin is the active ingredient in the drugs, Mycostatin and Nilstat, which are fungicidal and classified as polyenes. Polyenes are known to be toxic to the liver and not absorbed in the gut. Nystatin is most effective as an oral suspension to treat oral thrush, and as a cream for vaginal candidiasis, but it can be used as an ointment and powder on the skin as well.
According to "Fungal Infection: Diagnosis and Management," some natural, non-pharmaceutical preparations are effective at killing topical Candida albicans. These include hydrogen peroxide, colloidal silver, raw garlic, coconut oil, oil of oregano and clove oil.
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