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Good Antibiotics for Acne

Good Antibiotics for Acne Good Antibiotics for Acne Good Antibiotics for Acne

Acne vulgaris, the most common dermatologic disorder in the United States occurs primarily in young adults, according to "Harrison's Principles of Internal Medicine." A bacterium, Proprionobacterium acnes causes comedones, also known as whiteheads or blackheads. Treatment of acne includes either topical or oral antibiotics.

Topical Antibiotics

Topical antibiotics can treat mild acne. Topical clindamycin has a long history of successfully treating acne. Topical erythromycin can actively treat a broad spectrum of bacteria, including P. acnes. Both of these agents have equivalent efficacy against moderate acne. Sodium sulfacetamide can also treat acne.

Newer Topical Antibiotics

Topical picolinic acid, a novel zinc finger therapy appears safe and effective therapy for mild to moderate acne. According to the British Journal of Dermatology, a pilot study of 20 subjects with mild to moderate acne used topical 10 percent picolinic acid gel twice daily on their faces for 12 weeks. Fifteen subjects completed the study and a statistically significant reduction of 58.2 percent in mean total lesion count occurred.

According to the Journal of Drugs in Dermatology, dapsone, a drug used to treat leprosy and opportunistic infections in AIDS patients has also shown promise as a new acne treatment. In a study of 301 subjects treated with dapsone 5 percent gel combined adapalene gel or benzoyl peroxide gel applied twice daily for 12 weeks reduced the mean number of inflammatory lesions.

Oral Antibiotics

Tetracycline or erythromycin 250 to 1,000mg/day, mainstays of treatment for moderate to severe acne have antibacterial effects as well as anti-inflammatory effects. These two agents have comparable activity in treating acne.

According to the Journal of The American Medical Association, the main systemic antibiotics used to treat acne are tetracycline, doxycycline, minocycline, and erythromycin. Other oral antibiotics less commonly used are clindamycin, Cleocin, or sulfonamides, and Bactrim.

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