Oral Antibiotic For Acne Treatment Increases Pharyngitis Risk
Got Acne? Be careful with the treatment - this is what University of Pennsylvania researchers recommend. Recent work published in Archives of Dermatology denotes those having been prescribed oral antibiotic treatment have more often been a subject to pharyngitis (pharynx affection becoming the sore throat cause).
The researchers say that long-term antibiotics use have always been a debatable one for medical society. Since acne being widespread and antibiotics frequently used for its control, acne patients are almost perfect group for antibiotic long-term use investigation.
David J. Margolis, the leading researcher, and the team conducted both longitudinal and cross-sectional studies. The main aim was to determine whether the long-term antibiotic use in case of acne might cause pharyngitis.
Another goal was to disclose any linkage existing between oral antibiotics and group A streptococcus, bacterium which is considered to be the main cause of streptococcal illnesses. Some prior studies showed linkage between oral antibiotic treatment and increasing GAS (Group A Streptococcus) rates.
In both studies college students were involved. Every participant was to complete a questionnaire.
The Cross-Sectional Study
1) 10 of 15 students (66.6%) having received oral antibiotics told they got pharyngitis during the previous month;
2) Among 130 students suffering acne but not having the antibiotic treatment 47 (that is less than 40%) also got a pharyngitis case during the same period of time;
3) Summing up the whole group of those not taking antibiotics 82 of 251 that is 32.7% suffered pharyngitis in term of previous 30 days; 3 of 145 that is 2.1 % suffering acne appeared to have GAS. None of this group took antibiotics.
The Longitudinal Study
Longitudinal Study of investigation involved 576 participants of which 358 were female.
1) 36 of 576 (6.2%) took oral antibiotic treatment during the study progress. 11.3% of 36 appeared to get the pharyngitis symptoms.
2) 96 of 576 (16.6%) took topical antibiotics for acne during the study progress. 3.3% of 96 appeared to get the pharyngitis symptoms. Not a single participant of this group got GAS.
The researchers' conclusion is that the study shows distinct linkage existing between the factors examined. Those receiving oral antibiotic treatment for acne have three times more chances to get pharyngitis than those who uses some other cure type. Nevertheless true value of the investigation is still to be confirmed further by posterior researches.
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